GeneChaser 2.0 contains gene profiling of 33,192 biological and clinical conditions from ArrayExpress and GEO, including GEO series data. It enables users to limit the search on combination of different types of conditions, such as disease vs. control comparisons.
For microarray studies in public repositories, such as Gene Expression Omnibus (GEO), ArrayExpress, we now have information on the expression levels of essentially all genes in the genome, across many tested biological conditions, such as diseases, drug responses, individuals, and more.
GENECHASER is a gene-specific search tool across all of these experimental conditions. Give us a gene symbol, or Entrez Gene ID, and we will find all experimental conditions where that gene is significantly changed in expression level. You can see these results in a special graphical view.
You can search for a gene in a single species, or across all available species. You can also search for conditions associated with significant simultaneous changes in multiple genes. More instructions are here.
: Enter the gene symbol Nanog
and click Go.
Chen R., Mallelwar R., Thosar A., Venkatasubrahmanyam S., Butte A.J. (2008)
GeneChaser: identifying all biological and clinical conditions in which genes of interest are differentially expressed, BMC Bioinformatics 9:548